What is Mifepristone for:

This medication is a synthetic steroid, used alone or together with another medication, to end an early pregnancy (within 7 weeks of the start of a woman’s last menstrual period). It blocks the hormone needed for pregnancy to continue.

How does Mifepristone work:

It is also indicated for high blood sugar levels (hyperglycemia) in adults with endogenous Cushing’s syndrome.

How should Mifepristone be used:

If using to end a pregnancy: – This drug must be taken exactly as you have been told. – If using for high blood sugar: – Take with food. Swallow whole. Do not chew, break, or crush.

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Common side effects of Mifepristone :

Dizziness. Headache. Feeling tired or weak. Belly pain. Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. Not hungry. Loose stools (diarrhea). Vaginal bleeding. There may be more bleeding than from a heavy period. Low blood sugar. Signs include anger, shaking, a fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.

What do I do if I miss a dose?

If using to end a pregnancy: – Call your doctor to find out what to do. If using for high blood sugar: – Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take

when taking Mifepristone :

If you have an allergy to mifepristone or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

If you are taking a blood thinner or are on a long-term steroid, such as prednisone. If you are breast-feeding. If using to end a pregnancy: – If you have any of these health problems: Adrenal failure, bleeding problems, porphyrias, or pregnancy where the fertilized egg was not in a normal position. If you have an IUD (intrauterine device) in place. If you are not able to follow what your doctor gives you or you are not able to get to an ER (emergency room) if you need one. If you are more than 7 weeks pregnant. If using for high blood sugar: – If you have any of these health problems: – Change in the cells lining your uterus, endometrial cancer, or vaginal bleeding. If you do not have Cushing’s syndrome. If you are pregnant or may be pregnant.

When do I need to seek medical help?

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain. Bleeding a lot (soaking 1 pad per hour). Very bad dizziness or passing out. A fast heartbeat. Signs of low blood pressure. Signs of low blood sugar. Very bad belly pain. Very upset stomach or throwing up. Very loose stools (diarrhea). Weakness with or without belly pain and fever. Feeling very tired or weak. For women, period changes. These include lots of bleeding, spotting, or bleeding between cycles. Very bad muscle pain or weakness. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Mifepristone with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. – Taking them together can cause bad side effects. – Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Mifepristone :

Store in a cool, dry place away from the reach of children. – Medicines must not be used past the expiry date.

Pregnancy Category

Category X: Studies in animals or humans have demonstrated fetal abnormalities andor there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in the use of the drug in pregnant women clearly outweigh potential benefits.

Therapeutic Classification

Drugs Acting on the Uterus

Misoprostol

What is Misoprostol for:

This medication is a synthetic prostaglandin; prescribed for ulcer, labor induction, induced abortion, miscarriage, postpartum hemorrhage (blood loss during birth), and other gynecological uses.

How does Misoprostol work:

It reduces the acid secretion in the stomach.

How should Misoprostol be used:

It comes, as a tablet to take by mouth, with food. Adult: PO- The recommended dose is 200 mcg four times daily with food. If this dose cannot be tolerated, a dose of 100 mcg can be used.

Common side effects of Misoprostol :

Spotting, cramps, heavy periods, menstrual disorder, painful menstruation, and postmenopausal vaginal bleeding, and breast pain.

What do I do if I miss a dose?

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Misoprostol :

If you have an allergy to misoprostol or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are breast-feeding.

When do I need to seek medical help?

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Very upset stomach or throwing up. Very bad belly pain. Very loose stools (diarrhea). If taking to end a pregnancy: Upset stomach, throwing up, loose stools, or weakness with or without belly pain or fever. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Misoprostol with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. – Taking them together can cause bad side effects. – Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Misoprostol :

Store in a cool, dry place away from the reach of children. – Medicines must not be used past the expiry date.

Pregnancy Category

Category X: Studies in animals or humans have demonstrated fetal abnormalities andor there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in the use of the drug in pregnant women clearly outweigh potential benefits.

Therapeutic Classification

Antacids, Antireflux Agents & Antiulcerants, Drugs Acting on the Uterus

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